Actually, if you use the USSBS report and the later analyses, you would try to concentrate on German railyards as soon as possible. Coal was the keystone to the German economy (almost everything required coal inputs, since almost everything required vast amounts of heat), and coal had to be moved by rail. When the USAAF finally targeted the railyards in Germany during the Autumn of 1944, German industry went from peak production to collapse in 12 weeks - two months before any Allied soldier set foot on the east banks of the Rhine. Railyards were key, because trains need them for "creation", changing direction, and maintenance. As the railyards were bombed, the allocation of railcars to coal movement dropped precipitously, with combat unit supplies given priority for railcar use.
Of course, the question is whether the Allied air forces could have adequately targeted the railyards in Germany before the Summer of 1944. The transportation campaign entailed a very large number of sorties deep into Germany; there probably weren't enough escort fighters available until July or August 1944.
Fuel production and stockpiling actually continued through the end of the war, albeit at a much reduced rate; it just couldn't be delivered to its users. Now, production of synthetic aviation fuel was seriously impacted in late 1944 by Allied bombing of specific plants, but these aren't differentiated in the game from the plants producing standard grade fuel for motor vehicles. A recently published book, The Secret Horsepower Race (Callum Douglas), gives a very illuminating account of the fuel problems experienced by the German aviation industry throughout the war.
The fate of one "industry" not identified in the game, electrical power generation, so terrified the German leaders that reports of any damage to it could only be conveyed through hard copy reports, for fear that Allied intelligence would intercept wire and airwave transmissions. After the war, city leaders in Berlin told Allied interviewers that they could have shut down all operations in the city environs in just one air raid. US Air Force planners apparently took this to heart, because electric power facilities have been a priority target ever since.