From: Melbourne, Australia
so i would not really bank on beating brother vs. brother. even if you were to execute some daring feat of air tactics you'll still likely get slaughtered as the flankers enter their HOB WEZ and spray you down with archers.
I have been on a bit of a kick about this lately.
With Brother Against Brother in particular and operations in general, there is an urge to get out and fight the enemy because they're there. When you're up against superior opposition this is, of course, going to result in high casualties if you fight the enemy on their terms.
Like Cik mentioned, in CMANO the best results are obtained by analysing your opponents capabilities versus your own. In the example of Brother Against Brother you have Kfirs with a short range AAM (all-aspect IIRC, could be wrong on that though) versus F-16s and SU-27s on the other side, some of which have medium range SARH AAMs. If you try to knock them off piecemeal as they're on CAP, you can pretty much guarantee that you will lose all of your aircraft. Given the difference in capabilities, this is to be expected.
The mission however is to knock out a rebel camp. If you resist the temptation to go shoot enemy planes just because they're in the air, and instead use your all of your fighters at once to screen your attack aircraft going in to bomb the camp, then the scenario that some have called 'impossible' actually becomes quite easy. You might lose 2-3 Kfirs but you'll easily bomb the camp and win the mission.
Another good example is F/A-18As with AIM-120Bs vs Rafales with MICA EM/IRs in SIMEX. If you go up against the Rafales in air-to-air combat, you are almost certainly going to lose 2-3 Hornets for every Rafale you shoot down. On the other hand you have lots of strike aircraft, and a decent naval gunfire capability. Much better results come from destroying the Rafales on the ground using NGS or an airstrike, usually more in the order of rougly 15 Rafales destroyed for every aircraft lost (or even 0 a/c losses if using NGS).
In broader terms, my point is that rather than just going to fight because the enemy is there, try to make sure you fight the enemy only when it suits you or is absolutely necessary, and always on your own terms as much as possible.
As for specific tactics when it comes to air-to-air engagements, there is one simple method that I use to good effect: offsetting elements in a line or echelon. Rather than having a single 4-ship group all together, I would use 2x2-ship groups, one trailing the other at ~25-50nm, offset around 45 degrees off the tail of the lead group. This allows you to engage enemies with the lead group, and then while they are maneuvering to engage they are open to shots from the tail group. You can also experiment with differences in altitude to exploit lack of look-down/shoot-down capability, or snap-up/down limitations with enemy missiles. The aim is to try to have one group in a firing position without being exposed to return fire. Even with bad matchups like F/A-18 vs Rafales you can end up getting even odds or better results, against inferior opponents you will often have no losses.