Because you're playing the AI, you can vary the turn length. I would suggest starting out on 1 day turns, until the "situation" stabilizes (later in '42). Then, you can switch to 2 day turns, or even 3 day turns if you're feeling confident. But be ready to switch back to 1 day turns for important operations or battles with the KB.
I'm starting Nov '45 in my first campaign game (as Allies, against the AI) -- I started it more almost 4 years ago. My work schedule generally prevents me from playing more than 2-2.5 hours in the evening and 4 hours per day on the weekend. Things really slowed down in '45, with all of the Allied air reinforcements -- a turn now takes at least 4 hours to complete, or two weeknights of real time. I've kept it on 1 day turns since the middle of '44, since I regularly rotate air groups for rest. I achieved auto-vic in Jan '45, but kept playing to see how the final air and land campaign plays out. I played with an active Chinese campaign, which really helps in the final years, since the AI is not very good at ground operations -- it is easy to pocket large Japanese formations when you go on the offensive in Burma in late '43.
I hope this doesn't scare you -- in the early years of the campaign I could sometimes get through two turns in 2 hours. Once you develop a routine for getting through all of the elements of a turn, they can go fairly quickly.