I don't think it's dead yet. After all you gotta ask yourself why do we still remember Duke after so many years, the game was a masterpiece in its days, we *all* loved it. Then you got to ask yourself, what selfrespecting company wouldn't want to make a game with the name "Duke Nukem" in it. So they screwed it up bigtime... this time, but I just can't wait to see what other company will pick up the pieces, and make the Duke we've all been waiting for. And yes maybe they screw that one up too.... (anyone remember John Romero of "Doom" fame?). My point being, this time it ended up in utter failure, hopefully next time they will have more luck.
And I don't think there has been a game like Duke since Duke released, nor do I see one in the nearby future. Lots of shooter around, good ones too, but one with "adult" tongue in cheek humor? One with attitude?
Damn, can't believe I've been waiting for 10 years... what a bummer.