SimCity Societies is VERY cartoony, so don't look at that.
The older SimCity 4 Deluxe is very nice for management and such, but will not give you the industrial management like the others. You could look at the rather old (but rather cheap) Capitalism or Capitalism 2 by Trevor Chan, which is a business sim. Industry Giant 2 is also older and a bit cheaper, but has a lot of industrial management (but this game WILL NOT work with certain types of nVidia graphics cards, a fact which will not likely change). Finally, there is the new version of City Life 2008, which is an update of the few years old City Life series. It is a city builder, but there is a lot of social planning needed to manage the different subcultures of people in your city, which do not get along together (much like a real city).
It isn't modern, and it is slightly cartoony, but the colonial sim 1701 A.D. is tons of fun. Also, if you like the Caribbean, you could try Port Royale, which is a heavy and hardcore trade sim set in the age of piracy.
"Neca eos omnes. Deus suos agnoscet!"
(Kill them all. God will know his own.)
-- Arnaud-Armaury, the Albigensian Crusade