I installed CMO on a newly built computer (i5 12th gen, integrated UHD 770 graphics, 32MB RAM) and I've been having my map screen replaced with a red X on white background every few minutes while playing. A window has popped up a couple of times with "Attempted to read or write protected memory. This is often an indication that other memory is corrupt." I've only seen this issue on Northern Fury 34, but that is because that is the only scenario I've tried on this PC. The music and sounds continue and seem to indicate the game is still running while this takes place, but attempting to load an autosave gets a "SytstemOutOfMemoryException" error. Restarting the game seems to fix the problem, but only for a few minutes.
I've tried restarting, running CMO as admin, removing Steam overlays and DirectWrite, reinstalling Steam, reinstalling CMO, reinstalling DirectX June 2010 runtimes, reinstalling graphics drivers, and reinstalling NET Framework 4 and 6.
Any ideas? What info do you need? Log file attached.