From: Kansas, USA
I've seen this before and experienced it myself. Is your computer a laptop or a desktop PC? I have both with Vista64 at home and I also have XP64 at the office.
I would first use the Windows Update to get every available update and reboot a few times in between each update. Sometimes Microsoft will reboot automatically for the updates to take effect.
Next get your info on your video card and Update the video card drivers. you may need to set this on the lowest resolution at first i.e. 800x600. There are some settings in your display properties i.e. hardware acceleration and enable write combining. these may need to be set lower or turned off depending on the type of video you have.
last thing to adjust. In Vista there are some settings to control the Start Menu Bar Pop-up. It had settings that would enable the Programs List with fade effects, Icon shadows, extra color enhancements, and etc... I turned this off and reset it to the most basics.
Do you have any special screen savers or other programs that could adjust your desktop display automatically? you may want to disable that for now.
When I got my laptop with Vista, I reset my display back to the very basics without any of the "extras". I wanted performance and speed, for my games, instead of the fancy graphics visuals for my desktop. I also wanted to free up as much RAM memory for my games...
on a side note: Did you have any AV running when you installed the game? sometimes it might not want to write files to your system if its trying to scan them for a virus. you may want to try to re-install with out running your Anti-virus. if your worried about a virus, run a check on your system first, get it clean. Then unplug our network cable or turn off your wireless connection, and install UV. See if UV runs properly.
hope this helps.